ORTHOBIOLOGICS

Orthobiologic therapies have emerged as a revolutionary field in regenerative medicine, offering innovative solutions for active professionals seeking effective and natural approaches to heal orthopedic conditions. Orthobiologics refer to substances derived most commonly from blood or fat which contain bioactive components that stimulate and accelerate the natural healing processes. A stem cell is the elusive cell of interest when harvesting tissue for orthobiologics but ongoing research suggests that growth factors and not the actual cells are responsible for the positive effects on inflammation and healing.  These therapies aim to harness the body’s innate regenerative potential, offering a safe and effective alternative to traditional treatments for orthopedic conditions.

Platelet Rich Plasma (PRP)

Platelet-rich plasma (PRP) is created from peripheral blood (venipuncture) and placing the blood into a centrifuge to separate into layers. In this manner, the layer with the platelets and growth factors are isolated, thereby creating PRP. This concentrated product may then be delivered back to the patient at the location requiring treatment.

Bone Marrow Aspirate Concentrate (BMAC)

Blood is drawn via special needle while under local anesthesia from the patient’s bone (typically the pelvis) and prepared in a centrifuge to concentrate and isolate the stem cells. This concentrate may then be delivered back to the patient in the area of interest.

Adipose Tissue

Fat derived stem cells are prepared from the subcutaneous fat tissue, typically from the torso area. Fat cells are isolated in utilizing techniques analogous to blood preparation and the isolate is injected back into the patient in the area under treatment.

Amniotic Tissue

Placental tissue and fluid is currently the only FDA acceptable source of exogenous cells and soluble factors. As an embryonic source it has a high potential for active stem cells and/or the sought after helpful soluble factors. This source obviates the need for harvesting the patient’s own blood or fat. Only FDA approved products are considered for use.

Frequently Asked Questions

OrthoBiologic therapies are typically denied under insurance as providers consider them experimental, investigational, and/or not medically necessary. There are exceptions and with future research on outcomes will likely change.

Pricing is subject to material costs and possible facility fees.  Given that orthobiologics are not typically covered by insurance a one time up front payment is available which is subject to change based on material/supply costs.

PRP – 750 (one joint)

BMAC – ~3500 (one joint)

BMAC – ~5000 (two joints)

Extremely low risks given harvest and application is via needle.  Nonetheless as with any procedure there is risk for bleeding, infection, nerve injury or increased pain.

30 minutes or less. Blood (or fat) harvest take minutes and the centrifuge process take approximately 15 minutes.  Once prepared the injection is given commonly under ultrasound guidance.

Patients commonly note improvement within 6 weeks. Recovery time is dependent on the area being treated, the chronicity of the injury and various lifestyle factors.

Unknown. Outcomes research is ongoing.  For PRP there is suggestion of improvements outwards of 6 months and even some studies showing benefit beyond 1 year.

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